The immune system consists of several organs in the body including spleen, tonsils, bone marrow, and lymph nodes. These organs produce and release immune cells, which in turn fight off attacking bodies called antigens such as bacteria, viruses and cancer cells.
One of the most important functions of the natural immune system is to protect the body from infection. So, if the person is infected by any of the following:
These conditions can be explained as immunodeficiency, a condition in which the ability of the immune system to resist disease is impaired.
Most immunodeficiencies are acquired (secondary immunodeficiency), but some children are born with immune system problems (primary immunodeficiency) caused by inherited defects in the immune system, known as primary immunodeficiency. Many of these rare diseases appear in childhood, but they may appear in adulthood in some cases.
Primary immunodeficiency diseases develop as a result of defects in the genes that control the immune system and are therefore inherited. These diseases can be classified into four groups according to the affected part of the immune system:
When should I suspect that my child has a genetic immunodeficiency?
How we can diagnose the disease?
History and clinical examination.
Complete blood test, designed to study the number and function of immune cells.
Prenatal examination: for couples with a previous child diagnosed with primary immunodeficiency, and the gene that causes the disease has been identified, in which case a sample is taken from the amniotic fluid.
Treatment of primary immunodeficiency disease is divided into:
Treatment of infection as it occurs:
Antibiotics are used either for treatment or to prevent infection and in some cases, intravenous antibiotics are used. This is in addition to treatment of symptoms of pain or hyperthermia.
Strengthen the immune system based on the type of disease: